Regioselective synthesis of medium-sized bicyclic butenolides by Lewis acid catalyzed cyclization of cyclic 1,3-bis(trimethylsilyloxy)-1,3-butadienes with oxalyl chloride

Langer, P.P.LangerSaleh, NNRNNRSaleh2018-11-072018-11-072000https://resolver.sub.uni-goettingen.de/purl?gro-2/25642[GRAPHICS] A new strategy for the synthesis of medium-sized bicyclic gamma-alkylidenebutenolides is reported which involves Me3SiOTf-catalyzed cyclization of cyclic 1,3-bis(trimethylsilyloxy)-1,3-butadienes with oxalyl chloride.Regioselective synthesis of medium-sized bicyclic butenolides by Lewis acid catalyzed cyclization of cyclic 1,3-bis(trimethylsilyloxy)-1,3-butadienes with oxalyl chloridejournal_article10.1021/ol006419b000089831900022