Tzimas, ChristosChristosTzimasTerrovitis, JohnJohnTerrovitisLehnart, Stephan ElmarStephan ElmarLehnartKranias, Evangelia G.Evangelia G.KraniasSanoudou, DespinaDespinaSanoudou2018-05-072018-05-072015https://resolver.sub.uni-goettingen.de/purl?gro-2/14624Aberrant calcium signaling is considered one of the key mechanisms contributing to arrhythmias, especially in the context of heart failure. In human heart failure, there is significant down-regulation of the sarcoplasmic reticulum (SR) protein junctin, and junctin deficiency in mice is associated with stress-induced arrhythmias.enCalcium/calmodulin-dependent protein kinase II (CaMKII) inhibition ameliorates arrhythmias elicited by junctin ablation under stress conditionsjournal_article10.1016/j.hrthm.2015.03.04325814413