Selenium-Catalyzed C(sp(3))-H Acyloxylation: Application in the Expedient Synthesis of Isobenzofuranones

Kraetzschmar, FelixFelixKraetzschmarKassel, MartinMartinKasselDelony, DanielDanielDelonyBreder, AlexanderAlexanderBreder2018-11-072018-11-072015https://resolver.sub.uni-goettingen.de/purl?gro-2/37143Oxidative Se-catalyzed C(sp(3))H bond acyloxylation has been used to construct a diverse array of isobenzofuranones from simple ortho-allyl benzoic acid derivatives. The synthetic procedure employs mild reaction conditions and gives high chemoselectivity enabled by an inexpensive organodiselane catalyst. The presented approach offers a new synthetic pathway toward the core structures of phthalide natural products.Selenium-Catalyzed C(sp(3))-H Acyloxylation: Application in the Expedient Synthesis of Isobenzofuranonesjournal_article10.1002/chem.20140629025808950000353348100008