Ackermann, LutzLutzAckermannKaspar, Ludwig T.Ludwig T.Kaspar2018-11-072018-11-072007https://resolver.sub.uni-goettingen.de/purl?gro-2/50754An efficient methodology for the indirect anti-Markovnikov hydration of unsymmetrically substituted terminal and internal alkynes is based on TiCl4-catalyzed hydroamination reactions. Its application to ortho-alkynylhaloarenes, followed by a copper-catalyzed O-arylation, provides flexible access to substituted benzo[b]furans.TiCl4-Catalyzed indirect anti-markovnikov hydration of alkynes: Application to the synthesis of benzo[b]furansjournal_article10.1021/jo070887i17629343000248344400026