Böhrnsen, FlorianFlorianBöhrnsenGodek, F.F.GodekKiesel, J.J.KieselKramer, Franz-JosefFranz-JosefKramerBrockmeyer, PhillippPhillippBrockmeyerSchliephake, HenningHenningSchliephake2018-06-252018-06-252017-05https://resolver.sub.uni-goettingen.de/purl?gro-2/15132TGF-β1 signaling modulates epithelial mesenchymal transitions (EMT) of head and neck squamous cell carcinoma (HNSCC). Bone marrow mesenchymal stromal cells (BMSC) are able to exert a regulating influence on the expression of markers of EMT in HNSCC cells. It was thus the aim of this study to test the hypothesis that TGF-β1 modulates the interactions of tumor transition between BMSCs and HNSCC, affecting the expression of E-cadherin, Vimentin, Snail, Twist, MMP14 and beta-catenin. Furthermore, we analyzed alterations in the AKT-signaling of tumor and stroma cells.enjournal_article10.1016/j.jcms.2017.02.00928318921626954