Do Not Underestimate Nucleotide Excision Repair: It Predicts Not Only Melanoma Risk but Also Survival Outcome

Emmert, SteffenSteffenEmmertKraemer, Kenneth H.Kenneth H.Kraemer2018-11-072018-11-072013https://resolver.sub.uni-goettingen.de/purl?gro-2/29575Nucleotide excision repair (NER) removes UV-induced DNA damage and other bulky DNA lesions, thereby maintaining genomic integrity. Dr Qingyi Wei's group demonstrated over the last decade that NER fidelity and single-nucleotide polymorphisms (SNPs) in NER genes constitute melanoma risk biomarkers. In this issue, Li et al. provide evidence that SNPs in NER genes may also predict melanoma survival.Do Not Underestimate Nucleotide Excision Repair: It Predicts Not Only Melanoma Risk but Also Survival Outcomejournal_article10.1038/jid.2013.7223760049000320428400006