Rinderspacher, B. ChristopherB. ChristopherRinderspacherSchreiner, Peter R.Peter R.Schreiner2018-11-072018-11-072004https://resolver.sub.uni-goettingen.de/purl?gro-2/48469Empirical rules based on chromophores, although beautifully simple, turn out to be too constrained to be of general use. This computational study of selected 3-methylhexane and camphor derivatives demonstrates the limitations of focusing on chromophores. We conclude that in a hybrid of experiment and theoretical computation lies the future of determining absolute configurations.journal_article10.1021/jp036256j000220724300005