Switching the Reaction Mode of 4-Methoxycarbonyl-4-chloro-5-spirocyclopropaneisoxazolidines by N-Aryl Substitution

Cicchi, StefanoStefanoCicchiRevuelta, JuliaJuliaRevueltaObjartel, InaInaObjartelde Meijere, ArminArminde MeijereBrandi, AlbertoAlbertoBrandi2018-11-072018-11-072010https://resolver.sub.uni-goettingen.de/purl?gro-2/193974-Methoxycarbonyl-4-chloro-5-spirocyclopropaneisoxazolidines, easily obtained by in situ cycloadditions of nitrones to methyl 2-chlorocyclopropylideneacetate and 2-chlorospiropentylideneacetate, in contrast to their known thermal rearrangements leading to delta-lactams, undergo rearrangement to their respective tetrahydropyridones, when the nitrone nitrogen is substituted by an aryl moiety.Switching the Reaction Mode of 4-Methoxycarbonyl-4-chloro-5-spirocyclopropaneisoxazolidines by N-Aryl Substitutionjournal_article10.1055/s-0030-1258136000280567600009