Jin, YulanYulanJinFotso, SergeSergeFotsoYongtang, Z.Z.YongtangSevvana, MadhumatiMadhumatiSevvanaLaatsch, HartmutHartmutLaatschZhang, W.W.Zhang2018-11-072018-11-072006https://resolver.sub.uni-goettingen.de/purl?gro-2/26868A new sulfur-containing guanidino derivative, halichondria sulfonic acid (1) showing anti-HIV-1 activity, and halistanol trisulfate (2) with anti-tumor activity have been isolated from the marine sponge Halichondria rugosa Ridley & Dendy collected in the Chinese Southern Sea. The structure of 1 was elucidated by analysis of spectroscopic and crystal data.Halichondria sulfonic acid, a new HIV-1 inhibitory guanidino-sulflonic acid, and halistanol sulfate isolated from the marine sponge Halichondria rugosa Ridley & Dendyjournal_article10.1080/1478641060087974817127667000242898600016