Umbraculolide E, a new briarane diterpenoid from the gorgonian Gorgonella umbraculum

Abstract

A new briarane diterpenoid, umbraculolide E (1) has been isolated from the gorgonian Gorgonella umbraculum besides the known briarane diterpenoids, juncellin, umbraculolides A and D, and a steroid 22-acetoxy-3,25-dihydroxy-16-24,20-24-bisepoxy-(3 beta,16 alpha, 20S, 22R, 24S)-cholest-5-ene. The structures of the compounds were elucidated from their spectral data.