Domino C-H/N-H Allylations of Imidates by Cobalt Catalysis

Abstract

The domino C-H/N-H allylation of aryl imidates was accomplished by a versatile cobalt(III) catalyst. In contrast to a tandem rhodium/palladium catalysis approach, an operationally simple cationic cobalt complex proved effective in the step-economical C-H/N-H functionalization of imidates to directly provide expedient access to decorated vinyl isoquinolines by kinetically relevant C-H activation.