Polymer-assisted synthesis of ethyl 2-amino-4,6-diarylpyrimidine-5-carboxylates

Abstract

Nine novel ethyl 2-amino-4,6-diarylpyrimidine-5-carboxylates have been synthesized in modest to good yields by a five-step procedure that involves building of the heterocyclic moiety on a solid support derived from Merrifield’s resin and final displacement with an amine.