Paediatric Patient with Multiple Sclerosis and High Disease Activity

Abstract

We describe a boy with first symptoms of childhood multiple sclerosis (MS) at the age of 11 years. The diagnosis MS was established after the second attack and a disease-modifying therapy was started with glatiramer acetate (Copaxone (R)). Due to high frequency of relapses and a progressing lesion load in cerebral MRI a conversion to interferon beta-1b (Betaferon (R)) was initiated and well tolerated. After a short stable period of disease further progression of MS has now occurred.