Publication:
Comparative analyses of glycerotoxin expression unveil a novel structural organization of the bloodworm venom system

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dc.bibliographiccitation.artnumber64
dc.bibliographiccitation.issue1
dc.bibliographiccitation.journalBMC Evolutionary Biology
dc.bibliographiccitation.volume17
dc.contributor.authorRichter, Sandy
dc.contributor.authorHelm, Conrad
dc.contributor.authorMeunier, Frederic A.
dc.contributor.authorHering, Lars
dc.contributor.authorCampbell, Lahcen I.
dc.contributor.authorDrukewitz, Stephan H.
dc.contributor.authorUndheim, Eivind A. B.
dc.contributor.authorJenner, Ronald A.
dc.contributor.authorSchiavo, Giampietro
dc.contributor.authorBleidorn, Christoph
dc.date.accessioned2023-03-21T12:22:36Z
dc.date.available2023-03-21T12:22:36Z
dc.date.issued2017-03-04
dc.description.abstractWe present the first molecular characterization of glycerotoxin (GLTx), a potent neurotoxin found in the venom of the bloodworm Glycera tridactyla (Glyceridae, Annelida). Within the animal kingdom, GLTx shows a unique mode of action as it can specifically up-regulate the activity of Cav2.2 channels (N-type) in a reversible manner. The lack of sequence information has so far hampered a detailed understanding of its mode of action.
dc.identifier.doi10.1186/s12862-017-0904-4
dc.identifier.pmid28259138
dc.identifier.urihttps://resolver.sub.uni-goettingen.de/purl?gro-2/123017
dc.item.fulltextWith Fulltext
dc.language.isoen
dc.relation.eissn1471-2148
dc.titleComparative analyses of glycerotoxin expression unveil a novel structural organization of the bloodworm venom system
dc.typejournal_article
dc.type.internalPublicationyes
dspace.entity.typePublication

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