Browsing by Author "Blanco, L."

Background and Objectives A multicentre trial was set up to evaluate the performance of a new leucodepletion. protocol. Materials and Methods Filtration at high haematocrit was started during collection of red blood cell (RBC) products by apheresis with Trima. SAG-M was added after filtration through the filter. Haematocrits and haemoglobin of the filtered RBCs were measured. Residual leucocytes were determined by Nageotte counting. Results One-hundred and forty seven procedures were carried out. The haematocrit and haemoglobin contents were 57.3 +/- 3.0% and 55.1 +/- 4.3 g/unit, respectively. All products showed low residual leucocyte levels (less than or equal to 0.75 X 10(6)/unit; 99.31% < 1 X 10(6)). Conclusion Immediate, on-line, high-haematocrit filtration of red cells collected on Trima resulted in leucoreduced RBCs, which met the AABB and Council of Europe criteria.